Bupropion-naltrexone (Contrave)
Bupropion-naltrexone (Contrave). CONTRAVE is a weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or more (obese), or adults with a BMI of 27 kg/m2 or more (overweight) with at least one weight -related medical problem, such as high blood pressure, high cholesterol, or type 2 diabetes, to lose weight and keep it off.
CONTRAVE should be use with a low calorie diet and increase physical activity.
It is not known if CONTRAVE is safe and effective when taken with other prescription, over-the-counter or herbal medicines for weight loss.
One of the ingredients in CONTRAVE, bupropion, may increase the risk of suicidal thoughts in children, adolescents, and young adults. Patients on CONTRAVE should be monitor for suicidal thoughts and behaviors. Serious neuropsychiatric adverse effects have been reported in patients taking bupropion to stop smoking. CONTRAVE is not approve for use in children under 18 years of age.
CONTRAVE® is the number one prescribe weight loss pill.
Stop taking CONTRAVE and call a healthcare professional immediately if you experience any of the following symptoms, especially if they are new, worsen, or are worrisome: thoughts of suicide or death; suicide attempts; depression; anxiety; feeling agitated or restless; panic attacks; difficulty sleeping (insomnia); irritability; aggression, anger, or violence; acting on dangerous impulses; an extreme increase in activity and speech (mania); other unusual changes in behavior or mood.
Do not take CONTRAVE if you have uncontrolled high blood pressure; have or have had seizures; use other medicines containing bupropion, such as WELLBUTRIN, APLENZIN or ZYBAN; have or have had an eating disorder; are addicted to opioid painkillers or use opioid cessation medicines, such as methadone or buprenorphine, or are in opioid withdrawal; they drink a lot of alcohol and suddenly stop drinking; are allergic to any ingredient in CONTRAVE; are pregnant or planning to become pregnant.
Before taking CONTRAVE, tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Do not take any other medicines while you are taking CONTRAVE unless your doctor says it is okay.
Buy bupropion-naltrexone (Contrave) online
Tell your doctor about all your medical conditions, including if you have: depression or other mental illness; attempted suicide; seizures Head trauma; tumor or infection of the brain or spine; low blood sugar or liver or kidney sodium problems; High blood pressure; heart attack, heart problems, or stroke; eating disorder; heavy drinking of alcohol; prescription or illicit drug abuse; you are 65 years of age or older; diabetes; pregnancy; or breastfeeding.
CONTRAVE can cause serious side effects, including:
Convulsions There is a risk of convulsions when taking CONTRAVE. If convulsions occur, stop taking CONTRAVE and tell your doctor immediately. Risk of opioid overdose. Do not take large amounts of opioids, including opioid-containing medicines such as heroin or prescription painkillers, to try to overcome the opioid-blocking effects of naltrexone. Sudden withdrawal of opioids. Do not use any type of opioid for at least 7 to 10 days before starting CONTRAVE. Severe allergic reactions Stop taking CONTRAVE and seek immediate medical attention if you have signs and symptoms of severe allergic reactions: skin rash, itching, hives, fever, swollen lymph nodes, painful sores in the mouth or around the eyes, swelling of the lips or tongue, chest pain . or difficulty breathing.
Increased blood pressure or heart rate.
Liver damage or hepatitis. Stop taking CONTRAVE if you have symptoms of liver problems: stomach pain lasting more than a few days, dark urine, yellowing of the white part of the eyes, or tiredness.
Manic episodes
Visual problems (narrow-angle glaucoma). One and the same
The New Weight Loss Pill on the Market, Is Contrave Any Good?
The appeal of the diet pill doesn’t seem to have waned at all. A new compound, which goes by the name Contrave, has join dozens of other brands and compounds already on the shelves and has just been approve by the FDA. It was formulated with two different drugs at the same time. So here we are again – is it safe and does it really do what it should?
It really is an interesting combination for a diet pill. Contrave contains two well-known drugs, reused for a new purpose. It contains bupropion, the familiar antidepressant, and naltrexone, a drug that people who have been through alcohol rehab are familiar with. So why would anyone want to treat weight loss with antidepressants and rehab drugs?
The antidepressant is to help increase the levels of dopamine that you have in your brain. What happens is it suppresses your appetite and makes you feel much more energetic. And the alcohol detox, on the other hand, just makes food less tasty. Even if the antidepressant allows you to eat a little bit, you won’t really like what you’re eating and you won’t want to eat as much. Now, that sounds like some kind of special hell.
So does it really work? They did several one-year studies with thousands of obese people. They found that people who took Contrave lost maybe 4% more weight than people who took the placebo. As for the FDA, if a new drug doesn’t make you lose weight at least 5% better than someone taking a sugar pill, it’s not a good enough drug. However, in some of their trials, they found that their participants lost 5% more. And the drug is approve by the FDA.
So this is not a weight loss pill that promises sensational results. But is it at least safe? In tests, some people found they had a slight increase in blood pressure when they took Contrave, at least for the first two months. People who take the drug often also complain of nausea, difficulty with constipation and constant headaches. The problem with Contrave is that it does not lead to heart disease like Fen-Phen or Meridia.
Is it a safe drug or not? No one really knows what it does in the long term; In the short term, however, its effects on weight loss are quite encouraging. You will probably want to discuss this with your doctor.
A New Prescription Diet Pill
There is a new drug that is one step away from being approved for the treatment of obesity. The name of this drug is Contrave ™. It is a formulation of other drugs, part bupropion and part naltrexone. When taken together in specific amounts and in a sustaine-release formulation, so to significantly reduce weight in obese patients. The manufacturer of Contrave is Orexigen Therapeutics, which has already invested years of research and a lot of money and time developing and testing almost everything that can be tested with this combination. Thousands of patients have taken part in these studies, some lasting as long as a year to ensure that the drug itself is effective compare to a placebo, as well as safe enough for the public. Bupropion-naltrexone (Contrave)
As a result, it was recently submitted to the FDA for approval and in December 2010, the FDA committee panel reviewe the positives and negatives of this drug and then voted on its recommendation. The vote was 13-7 in favour of its approval. January 31, 2011 is the date the FDA has set to evaluate Contrave and decide whether to approve it or not. In most cases, the FDA will listen to what its panel has said about a new drug and follow its advice. However, it should be noted that you are not require to do so and, in theory, you still cannot approve Contrave. Bupropion-naltrexone (Contrave)
The combination of bupropion and naltrexone is interesting. Bupropion is an antidepressant that works differently to many of the usual SSRI antidepressants, but has shown the side effect of many of the weight loss medications. It has been prescribe by some doctors as a weight loss drug, but it has been done “off-label”, meaning that a regulatory body has never approve the use of bupropion for this use. Bupropion has also been use to help people stop smoking / nicotine addiction. Naltrexone is a drug more often prescribe to help patients overcome drug and alcohol related addictions. When these two are combine, researchers have found that naltrexone helps maintain weight loss where bupropion often begins to slow. The idea of a combination of weight loss drugs is not new, there are a few others being tested to treat obesity, including Qnexa and Empatic.
If Contrave ends up being approve, it will be available through your prescription. You will probably also need to show obesity-related health problems and a high BMI (body mass index) to get this prescription. There may also be some side effects you may experience when taking the weight loss drug Contrave [http://www.new-dietpills.com/]. The most common ones discovered during the test were nausea, headaches and constipation, which usually occur at the beginning of taking it. If you are interested in such treatment, talk to your doctor about what to expect when taking this or any other prescription diet pill and what else can be done to help you lose weight. Bupropion-naltrexone (Contrave)
Reviews
There are no reviews yet.